Ondansetron (on- dan -se-tron), Ondissolve ODF (trade name Zofran (trade name Zofran ODT (trade name Zuplenz (trade name classification, therapeutic: antiemetics, pharmacologic: five ht3 antagonists, pregnancy Category:. Indications, prevention of nausea and vomiting associated with highly or moderately emetogenic chemotherapy. Oral: Prevention max dose of zofran of nausea and vomiting associated with radiation evention and treatment of postoperative nausea and vomiting. Action, blocks the effects of serotonin at 5-HT3receptor sites (selective antagonist) located in max dose of zofran vagal nerve terminals and the chemoreceptor trigger zone in the CNS. Therapeutic effects, decreased incidence and severity of nausea and vomiting following chemotherapy or surgery. Pharmacokinetics, absorption: IV administration results in complete bioavailability; 100 absorbed following oral administration. Metabolism and Excretion: Extensively metabolized by the liver zofran effects on baby (primarily by CYP3A4 5 excreted unchanged by the kidneys. Half-life: Adults.55.5 hr; Children 5 mo12.9. Time/action profile (antiemetic effect route. Onset, pEAK, duration, pO, IV rapid 1530 min 48 hr, iM rapid 40 min unknown Contraindications/Precautions Contraindicated in: Hypersensitivity;Orally disintegrating tablets contain aspartame and should not be used in patients with phenylketonuria;Congenital long QT syndrome;Concurrent use of apomorphine. Use Cautiously in: Hepatic impairment (daily dose not to exceed 8 zofran dosage im mg Abdominal surgery (may mask ileus Obstetric / Lactation / Pediatric: Pregnancy, lactation, or children 3 yr (PO) or 1 mo (parenteral) (safety not established). Adverse Reactions/Side Effects Central nervous system headache ( most frequent ) dizziness drowsiness fatigue weakness Cardiovascular torsade de pointes (life-threatening) QT interval prolongation Gastrointestinal constipation ( most frequent ) diarrhea ( most frequent ) abdominal pain dry mouth liver enzymes Neurologic extrapyramidal reactions Interactions Drug-Drug. Carbamazepine, phenytoin, and rifampin may levels. Route/Dosage Oral (Adults) Prevention of nausea/vomiting associated with highly-emetogenic chemotherapy 24 mg 30 min prior to chemotherapy. Oral (Adults and Children 11 yr) Prevention of nausea/vomiting associated with moderately emetogenic chemotherapy 8 mg 30 min prior to chemotherapy and repeated 8 hr max dose of zofran later; 8 mg q 12 hr may be given for 12 days following chemotherapy. Prevention of radiation-induced nausea/vomiting 8 mg 12 hr prior to radiation; may be repeated q 8 hr, depending on type, location, and extent of radiation. Prevention of postoperative nausea/vomiting 16 mg 1 hr before induction of anesthesia. Oral (Children 411 yr) Prevention of nausea/vomiting associated with moderately emetogenic chemotherapy 4 max dose of zofran mg 30 min prior to chemotherapy and repeated 4 and 8 hr later; 4 mg q 8 hr may be given for 12 days following chemotherapy. Intravenous (Adults) Prevention of chemotherapy-induced nausea/vomiting.15 mg/kg (max zofran side effects constipation dose 16 mg) 30 min prior to chemotherapy, repeated 4 and 8 hr later. Intramuscular Intravenous (Adults) Prevention of postoperative nausea/vomiting 4 mg before induction of anesthesia or postoperatively. Intravenous (Children 6 mo18 yr) Prevention of chemotherapy-induced nausea/vomiting.15 mg/kg (max dose 16 mg) 30 min prior to chemotherapy, repeated 4 and 8 hr later. Intravenous (Children 1 mo12 yr and 40 k g) Prevention of postoperative nausea/vomiting. Intravenous (Children 1 mo12 yr and 40 kg) Prevention of postoperative nausea/vomiting.1 mg/kg. Hepatic Impairment Oral Intramuscular Intravenous (Adults) Severe hepatic impairment Not to exceed 8 mg/day. Availability (generic available) Orally disintegrating tablets (contain aspartame)strawberry flavor: 4 mg, 8 mg Cost: Generic 4 mg 668.78 zofran and serotonin syndrome / 30, 8 mg 1,113.95 / 30 Oral soluble film (Zuplenz 4 mg, 8 mg Cost: All strengths.50 / 1 Tablets: 4 mg, 8 mg,. Assess patient for extrapyramidal effects (involuntary movements, facial grimacing, rigidity, shuffling walk, trembling of hands) periodically during therapy. Monitor ECG in patients with hypokalemia, hypomagnesemia, HF, bradyarrhythmias, or patients taking concomitant medications that prolong the QT interval. Lab Test Considerations: May cause transient in serum bilirubin, AST, and ALT levels. Potential Nursing Diagnoses Imbalanced nutrition: less than body requirements (Indications) Diarrhea (Side Effects) Constipation (Side Effects) Implementation First dose is administered prior to emetogenic event. Oral: For orally disintegrating tablets, do not attempt to push through foil backing; with dry hands, peel back backing and remove tablet. Immediately place tablet on tongue; tablet will dissolve in seconds, then swallow with saliva. Administration of liquid is not necessary. Intravenous Administration Administer undiluted (2 mg/mL) immediately before induction of anesthesia or postoperatively if nausea and vomiting occur shortly after surgery. Rate: Administer over at least 30 sec and preferably over 25 min. Intermittent Infusion: Diluent: Dilute doses for prevention of nausea and vomiting associated with chemotherapy in 50 mL of D5W,.9 NaCl, D5/0.9 NaCl, D5/0.45 NaCl.

How often can zofran be taken

The star of the motion sickness natural remedies line up has to how often can zofran be taken be ginger! It has been used as a treatment for max dose of zofran motion sickness for centuries (it's said to how often can zofran be taken have been first used by the ancient Chinese and although it doesn't work for everyone, a lot of people find it very effective indeed. Ginger (Zingiber officinale) is natural, widely available and cheap. What's more, it comes in numerous forms - from raw to capsules, from cookies to tea - so even if you're not a big fan of the taste, there's likely to be something you can take. And it works fast (some people find it has an almost instant effect! even after you have started to feel nauseous. Ginger and side effects, for most people, ginger is completely safe and side-effect free. However, it is contra indicative (can negatively interact) with certain medications, particularly blood thinners (e.g. Ginger should not be used by those taking blood thinners. If you are taking a course of medication, and/or if you are at all unsure if ginger is right for you, then consult your doctor. How to take ginger, ginger, of course, is widely available in its raw state (ginger root but as well as fresh, it can also be used dried, powdered and as a juice or oil. You'll find it available as supplements, pills and capsules, tea, candied, in drinks (ginger ale, ginger beer) and in sweets and cookies (ginger snaps and nuts). It is even available as an essential oil (see below). A piece of raw ginger root, the cheapest way how often can zofran be taken to take ginger is to simply buy a small piece of fresh raw ginger root in the supermarket (fresh produce section). Peel it and suck or chew a small cube or slice. Probably better not to swallow it though, as ginger can give a lingering aftertaste that many find unpleasant. Ginger pills, tablets and capsules, if raw ginger is a bit much for you, visit your local pharmacy to get ginger in dehydrated form as pills, capsules or chewable tablets. I find the chewable tablets work best for me, probably as the chewing action itself has a preventative effect against nausea (see. Basic "Dos and Don'ts" - 'Suck a hard candy / boiled sweet' section). Powdered ginger, found in supermarket spice sections, powdered ginger can also be effective, and half a teaspoon full can be taken in a glass of water (plain or fizzy) or apple juice. Mix in a little sugar how often can zofran be taken if you still have problems with the taste. Similarly, raw ginger root can be grated and boiled up to make a 'tea'. Strain off the grated pieces and drink the liquid either as it is, or with added sugar or honey. I find this better hot than cold, so take it along with you in a vacuum flask. Ginger candy, another option is to suck on a piece of candied ginger (also known as crystallized ginger available from good grocery and health food stores. Rather than chew the ginger, let zofran dissolving tablets it dissolve in your mouth. As with raw ginger, don't swallow too much of this, as it tends to 'repeat' on you. Pickled ginger ( gari, Japanese sushi ginger pickled ginger. Pickled ginger (or gari, Japanese sushi ginger) is available from Asian groceries and some health food stores.

Percocet and zofran

109 200 49 200 147 200 179 200 168 200 126 200 200 121 200 200 74 200 200 182 200 200 Lipitor Prevacid Zocor Nexium Zoloft Celebrex Zyprexa Neurontin Effexor XR Advair Diskus OxyContin Norvasc Wellbutrin SR Plavix Pravachol Vioxx Singulair Protonix Ambien Risperdal. A total of 531 drugs (3193 brand and generic names) are known to interact with. 199 major drug interactions (1455 brand and generic names) 323 moderate drug interactions (1694 brand and generic names) 9 minor drug interactions (44 brand and generic names). Show all medications in the database that may interact with Zofran (ondansetron). Check for interactions with Zofran (ondansetron). Type in a drug name and select a drug from the list. Common medications checked in combination with Zofran (ondansetron). Zofran (ondansetron) disease Interactions, there are 2 disease interactions with Zofran (ondansetron) which include: See Also, drug Interaction Classification. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Major, highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate, moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Minor, minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown, no information available. Do not stop taking any medications without consulting your healthcare provider. Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's percocet and zofran information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence percocet and zofran of a warning for a given drug or combination thereof in no way should be construed to indicate percocet and zofran that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. Does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist. Whether you are addicted to drugs, nicotine or alcohol, dealing with withdrawal percocet and zofran symptoms can be difficult and, when unsuccessful, can lead to relapse. Coping with cravings means instituting good habits that effectively circumnavigate your attention from the substance to the new, healthy practice. If youve tried to quit before, you know that this can be the worst part of beginning recovery. If youve relapsed in the past, you may not know that these feelings do not last forever. Getting past the first few days or weeks of withdrawal is often the hardest. Identifying Withdrawal Symptoms, drugs alter a persons ability to think clearly and exercise good judgment. Especially when experiencing withdrawal, the brain will try to rationalize just about any reason to make taking drugs a good idea. Withdrawal symptoms can include: Increased sensitivity to pain, irritability.

Zofran

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